How to use the pyramid.response.Response function in pyramid

def _register_name_unclear_error(self):
        payload = json.dumps({"status": 409, "code": "unexistent_error_code"}).encode()
        response_code = 409
        content_type = "application/json"
        return response.Response(
            payload, response_code, [("Content-Type", content_type)]
        )

def index(request):
        assert request.json == data
        assert request.text == json.dumps(data)
        assert not request.POST
        capture_message("hi")
        return Response("ok")

def change_status(request):
    topic_id = request.matchdict.get('topic_id')
    status = request.matchdict.get('status')
    
    default_status = ['publish', 'suspend', 'delete']
    if status not in default_status:
        return Response('This status not allow', status='500')
    
    topic = models.Topic.objects.with_id(topic_id)
    if topic is None:
        return Response('Not Found, topic title:%s'%topic_id, status='404 Not Found')
    
    topic.status = status
    topic.save()
    
    if status == 'delete':
        return HTTPFound(location=request.route_path('manager.topics.problem'))
    
    return HTTPFound(location=request.route_path('forums.topics.index'))

def update_auto(request: Request):
    car_id = request.matchdict.get('car_id')
    car = Repository.car_by_id(car_id)
    if car_id == '__first__':
        car_id = Repository.all_cars()[0].id

    if not car:
        msg = "The car with id '{}' was not found.".format(car_id)
        return Response(status=404, json_body={'error': msg})

    try:
        car_data = request.json_body
    except:
        return Response(status=400, body='Could not parse your post as JSON.')

    vm = UpdateAutoViewModel(car_data, car_id)
    vm.compute_details()
    if vm.errors:
        return Response(status=400, body=vm.error_msg)

    try:
        Repository.update_car(vm.car)
        return Response(status=204, body='Car updated successfully.')
    except:
        return Response(status=400, body='Could not update car.')

setting_disable_check = request.env.core.settings.get(sett_name, 'false').lower()
        if setting_disable_check not in ('true', 'yes', '1'):
            request.resource_permission(PD_READ)

        z = int(request.GET['z'])
        x = int(request.GET['x'])
        y = int(request.GET['y'])

        req = obj.render_request(obj.srs)
        img = req.render_tile((z, x, y), 256)

        buf = StringIO()
        img.save(buf, 'png')
        buf.seek(0)

        return Response(body_file=buf, content_type='image/png')

"""
    try:
        inbound = request.body
        inbound_json = json.loads(inbound)
        key = inbound_json["header"]["jwk"]
        body = json.dumps(
            {
                "key": key,
                "status": "good",
                "contact": ["mailto:cert-admin@example.com", "tel:+12025551212"],
            },
            sort_keys=True,
        )
    except:
        raise ValueError("invalid input")
    return Response(
        body=body,
        status_code=201,
        headers={
            "Link": ';rel="terms-of-service"',
            "Date": datetime.datetime.utcnow().isoformat(),
        },

from sqlalchemy.sql.functions import func
            mimetype, create_date, file_identity = File.default_db.query(
                File.mime_type, File.creation_date, file.file_identity
                ).filter_by(id=int(document_id)).first()
            size = path.getsize(File.path_of(file_identity))
            return Response(
                body=None, content_type=str(mimetype),
                content_length=size, last_modified=create_date)
    try:
        result = requests.head(url, timeout=15)
    except requests.ConnectionError:
        return Response(
            status=503,
            location=url)

    return Response(
        content_type=result.headers.get('Content-Type', None),
        status=result.status_code,
        location=result.url)

self.content = list(app_iter)
        self.index = 0

    def __iter__(self):
        return self

    def __next__(self):
        try:
            return self.content[self.index]
        except IndexError:
            raise StopIteration
        finally:
            self.index += 1


class SwitchProtocolsResponse(Response):
    """Upgrade from a WSGI connection with the WebSocket handshake."""

    def __init__(self, environ, switch_protocols):
        super().__init__()
        self.status_int = 101

        http_1_1 = environ['SERVER_PROTOCOL'] == 'HTTP/1.1'

        def get_header(k):
            key_map = {k.upper(): k for k in environ}
            return environ[key_map['HTTP_' + k.upper().replace('-', '_')]]

        key = websockets.handshake.check_request(get_header)

        if not http_1_1 or key is None:
            self.status_int = 400

}

    page.append(define.render('user/favorites.html', [
        # Profile information
        userprofile,
        # User information
        profile.select_userinfo(otherid, config=userprofile['config']),
        # Relationship
        profile.select_relation(request.userid, otherid),
        # Feature
        form.feature,
        # Favorites
        faves,
    ]))

    return Response(define.common_page_end(request.userid, page))

if r.raw.closed and r.next:
        body = r.next.body
    else:
        body = r.raw.read()
    if r.status_code < 400:
        commit_serial = int(r.headers["X-DEVPI-SERIAL"])
        xom.keyfs.wait_tx_serial(commit_serial)
    headers = clean_response_headers(r)
    headers[str("X-DEVPI-PROXY")] = str("replica")
    if r.status_code == 302:  # REDIRECT
        # rewrite master-related location to our replica site
        master_location = r.headers["location"]
        outside_url = request.application_url
        headers[str("location")] = str(
            master_location.replace(xom.config.master_url.url, outside_url))
    return Response(status="%s %s" %(r.status_code, r.reason),
                    body=body,
                    headers=headers)