How to use the ts-mockito/lib/ts-mockito.instance function in ts-mockito

beforeEach(() => {
        directorRepository = mock(DirectorRepository);
        serviceUnderTest = new DirectorService(
            instance(directorRepository),
        );
    });

        { provide: TranslateService, useFactory: () => instance(translateServiceMock) },
        { provide: Location, useFactory: () => instance(locationMock) },

        { provide: NoticeService, useFactory: () => instance(this.mockedNoticeService) },
        DatePipe

beforeEach(() => {
        httpClient = mock(HttpClient);
        customErrorHandler = mock(CustomErrorHandler);
        cacheCustomService = mock(CacheCustomService);
        const configSettings = {
            exlcudePath: ['categories12'],
            includePath: ['categories/computers12'],
            mockAllRequest: true
        };

        when(cacheCustomService.cacheKeyExists(anything())).thenReturn(true);
        when(cacheCustomService.getCachedData(anything())).thenReturn(configSettings);

        mockApiService = new MockApiService(instance(httpClient), instance(customErrorHandler), instance(cacheCustomService));
    });

        { provide: CategoriesService, useFactory: () => instance(categoriesServiceMock) },
        { provide: LocalizeRouterService, useFactory: () => instance(localizeServiceMock) }

        { provide: Location, useFactory: () => instance(locationMock) },
        { provide: ALWAYS_SET_PREFIX, useValue: true },

        { provide: HttpClient, useFactory: () => instance(httpClient) },
        { provide: REST_ENDPOINT, useValue: `${BASE_URL}/site` },

        { provide: Store, useFactory: () => instance(storeMock$) },
        ApiServiceErrorHandler,